Serum protein electrophoresis by CZE 2000 clinical capillary electrophoresis system

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Serum protein electrophoresis by CZE 2000 clinical capillary electrophoresis system.

We compared the automated Paragon 2000 clinical capillary zone electrophoresis (CZE) system with two manual methods, agarose electrophoresis (AGE) and cellulose acetate electrophoresis (CAE). Reference intervals in healthy adults were determined for each method. When compared with AGE and CAE, CZE gave substantially higher reference values for the alpha1-globulin fraction. With CZE, within-run ...

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Multicenter evaluation of the Paragon CZE 2000 capillary zone electrophoresis system for serum protein electrophoresis and monoclonal component typing.

Serum protein electrophoresis and typing of monoclonal components (MCs) are routine but time-consuming and technically demanding assays. We evaluated capillary electrophoresis (Paragon CZE 2000) for automation of the two assays. CZE and cellulose acetate electrophoresis gave similar data on 794 samples. Within-run and between-run CVs were < 2% for albumin and gamma-globulins and 4-7% for alpha ...

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Serum protein electrophoresis and immunofixation by a semiautomated electrophoresis system.

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Optimization of serum protein separation by capillary electrophoresis.

* Author for correspondence. 2. Lewellen U, McCurdy HH. A novel procedure for the analysis of drugs in whole blood by homegeneous enzyme immunoassay (EMIT). J Anal Toxicol 1988:12:260-4. 3. Manca D, Ferron L, Weber JP. A system for toxicological screening by capillary gas chromatography. Chin Chem 1989;35:601-7. 4. Hawks R, Chiang C, eds. Urine testing for drugs of abuse. NIDARes Monogr 73, Roc...

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CLINICAL APPLICATIONS Capillary Electrophoresis

Column Zorbax silica, 25 cm 4.6 mm internal diameter (7 m) S5W uncoated silica, 25 cm 4.6 mm internal diameter (5 m) Eluent Hexane}ethyl acetate, 95 : 5 CO2 modified with small amounts of methanol Flow rate 1.6 mL min 1 2 mL min 1 for 4 min, then gradient of 2 up to 5 mL min 1 thereafter held constant Programme Isocratic P"100 atm, T"403C; modifier, 1.5%min 1 from 10% to 30% thereafter held con...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1998

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/44.4.749